4bd2d66645 Prokaryotic genome regulation: a revolutionary paradigm. Updated set of predicted TFs We updated the set of computationally predicted TFs, based on recent work by Perez-Rueda et al. The clustering can be displayed as a collection of hierarchical trees (forest), where each tree represents a cluster with its global alignment of PWMs. Accepted October 19, 2015. Ishihama A. Nucleic Acids Res. These proteins can be classified in 78 different evolutionary families based on PFAM, CDD and Superfamily annotations.
In our manual curation, we considered only data supported by experimental evidence, with the large majority supported by strong evidence (i.e., based on RT-PCR), except for 10 sRNAs supported by microarray experimental data. COLOMBOS v2.0: an ever expanding collection of bacterial expression compendia. Abstract/FREE Full Text 33. Also in the same section, there is a link to display a circular browser (Figure 2), developed with the D3.js JavaScript library ( that integrates the information from families, the TFs and their PWMs. Curation is a bottleneck for facilitating the capability to digest the tsunami of genomic knowledge. We have updated the computationally predicted transcription factors, which total 304 (184 with experimental evidence and 120 from computational predictions); we updated our position-weight matrices and have included tools for clustering them in evolutionary families. Search for related content PubMed PubMed citation Articles by Gama-Castro, S. Major changes to the overall navigation and structure of the main pages have been made, offering more structured access to the data, based on the two dominant types of users: biologists, usually conducting individual search queries, and those interested in data collections. The TSSs are included in the file named High-throughput transcription initiation mapping.
Ranberna replied
469 weeks ago